The legality of CBD in the United States varies to a large extent based on its source:
CBD produced using hemp that contains less than 0.3% THC is legal on the federal level, but certain restrictions may be enforced by some states.
CBD produced by marijuana is still illegal on the federal level, but allowed in states where recreational or medical cannabis is legalized.
Laws across the world are quite diverse- in some countries, it is entirely illegal, in others, it is regulated, in a few countries, it is illegal. The local regulations are to be addressed before buying or traveling with CBD.
The significance of CBD in Wellness Today.
The capacity of CBD to offer therapeutic potential without intoxication is the secret behind its popularity.
It serves as a compromise between natural wellness and clinical research and provides the average
between those who are in need of relief without the side effects of the conventional pharmaceuticals and those who are willing to experience psychoactive effects of THC. A lot of the potential of CBD,
as we will explore in the following section lies in its interaction with the body regulation mechanisms.
How CBD Works in the Body
The Endocannabinoid System: A Lost Control.
To comprehend the mechanism of action of CD, it is necessary to take a first look at the endocannabinoid system (ECS) that is a complex of signaling networks in the human organism. The ECS is useful in controlling essential activities including:
Mood and stress response
Sleep cycles
Pain perception
Appetite and digestion
Immune system balance
The ECS uses naturally found compounds known as the endocannabinoids that attach to certain receptors (CB1 and CB2) located all over the body.
These are the interactions that ensure homeostasis or balance in the internal systems of the body.
In this study, the authors aim to explore the connection between CBT, the Endocannabinoid System, and cannabis use as a therapeutic tool.
CBD engages with the ECS in less direct and indirect mechanisms compared to THC that binds directly to CB1 receptors in the brain to have psychoactive effects. Researchers believe CBD:
Precludes the destruction of endocannabinoids, which ensures that they do not degrade as quickly.
Stimulates CB1 receptors and CB2 receptors, and does not bind strongly.
Activates non-cannabinoid receptors, e.g. serotonin (5-HT1A) and vanilloid (TRPV1) receptors,
involved in mood regulation, pain and inflammation perception.
This is one of the reasons behind the fact that CBD does not induce a high, yet has significant physiological effects.